senolyticnot-approved
FOXO4-DRI
FOXO4-D-Retro-Inverso
Overview
A promising senolytic peptide being researched for its potential to clear senescent ("zombie") cells to reverse aspects of biological aging. Showed dramatic results in aged mice.
Mechanism of Action
Disrupts the interaction between FOXO4 and p53 in senescent cells, triggering apoptosis (cell death) specifically in these damaged cells while leaving healthy cells unaffected.
Popular Research Uses
- Senescent cell clearance
- Anti-aging
- Longevity
- Tissue regeneration
Potential Side Effects
- Unknown - only animal data
- Potential immune effects
Warnings
- Extremely limited data
- Very expensive
- Only animal studies
- Unknown long-term effects
- Theoretical cancer concerns
Dosage Information
Experimental only. No established human dosing. Extremely expensive.