weight-lossapproved
Tirzepatide
Tirzepatide (Mounjaro/Zepbound)
Overview
A dual GIP/GLP-1 receptor agonist approved for type 2 diabetes (Mounjaro) and obesity (Zepbound). Shows superior weight loss results compared to semaglutide in trials.
Mechanism of Action
Activates both GIP and GLP-1 receptors, providing dual hormone action. This combination may provide enhanced metabolic benefits compared to GLP-1 alone.
Popular Research Uses
- Weight loss (up to 22% body weight in trials)
- Diabetes management
- Appetite control
- Metabolic health
Potential Side Effects
- Nausea and vomiting
- Diarrhea
- Decreased appetite
- Abdominal pain
- Constipation
Warnings
- Requires prescription
- Supply shortages common
- Similar risks to semaglutide
- Higher cost than semaglutide
- Limited long-term data
Dosage Information
Gradual dose escalation required. Higher doses show greater weight loss.