weight-lossapproved
Semaglutide
Semaglutide (Ozempic/Wegovy)
Overview
A GLP-1 receptor agonist approved by the FDA for type 2 diabetes (Ozempic) and chronic weight management (Wegovy). One of the most studied and widely used peptides.
Mechanism of Action
Mimics the GLP-1 hormone, which regulates appetite and food intake. Slows gastric emptying, increases insulin secretion, and acts on brain regions controlling hunger.
Popular Research Uses
- Weight loss
- Blood sugar control
- Appetite suppression
- Type 2 diabetes management
- Cardiovascular risk reduction
Potential Side Effects
- Nausea and vomiting
- Diarrhea or constipation
- Abdominal pain
- Fatigue
- Injection site reactions
Warnings
- Requires prescription
- GI side effects are common
- Contraindicated with history of medullary thyroid carcinoma
- May cause pancreatitis
- Muscle loss concerns without exercise
Dosage Information
Dose is gradually increased over weeks to minimize side effects.