AOD-9604 Dosing Protocol
AOD-9604 is a modified fragment of human growth hormone (amino acids 177-191) studied specifically for fat metabolism without the proliferative or diabetogenic effects of full-length GH. It has TGA approval in Australia as an oral supplement ingredient.
Key Points
Step-by-Step Guide
Set Standard Dose
Research protocols use 300-500 mcg/day subcutaneously. Some studies used oral doses of 1 mg/day, though oral bioavailability is lower.
Time Administration
Inject fasted, typically first thing in the morning. Wait 30-60 minutes before eating. Fasting enhances fat mobilization effects.
Select Injection Site
Subcutaneous injection near abdominal fat stores is common, though systemic absorption means site selection may not critically matter.
Run Protocol Duration
Research protocols typically run 12-20 weeks. Fat metabolism effects are gradual and require consistent long-term use to assess.
Track Body Composition
Use DEXA scans or calipers at baseline and 8-12 week intervals. Body weight alone is insufficient—track fat mass specifically.
Warnings & Precautions
- !Clinical trial results have been mixed—efficacy is not firmly established.
- !Not FDA-approved for any indication.
- !Effects are modest compared to GLP-1 agonists for weight loss.
- !Ensure product authenticity, as this is a commonly counterfeited peptide.
Frequently Asked Questions
How does AOD-9604 differ from growth hormone?
AOD-9604 is the fat-metabolizing fragment (aa 177-191) of GH without the growth-promoting or insulin-resistant effects. It selectively targets lipolysis pathways.
Is AOD-9604 effective for weight loss?
Clinical trials showed modest fat reduction. It is significantly less effective than GLP-1 agonists like semaglutide. Results vary and the evidence base is limited.
Can AOD-9604 be taken orally?
Oral formulations exist (TGA-approved in Australia at 1 mg), but oral bioavailability is lower than injectable. Most research protocols use subcutaneous injection.